Biomolecular markers as intermediate end points in chemoprevention trials of upper aerodigestive tract cancer

Assessment of DNA flow cytometry as a su

Assessment of DNA flow cytometry as a surrogate end point biomarker in a bladder cancer chemoprevention trial

✍ Silvia Bruno; Rosalba Torrisi; Massimo Costantini; Laura Baglietto; Vincenzo Fon 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB 👁 2 views

Although conventional cytology represents the most widely performed cytometric analysis of bladder cancer cells, DNA flow cytometry has, over the past decade, been increasingly used to evaluate cell proliferation and DNA ploidy in cells from bladder washings. We have investigated whether DNA flow cy