Biomarker Modulations in Children With Neuroblastoma Following Treatment With 131I-mIBG
β Scribed by Imber, B.S.; Olow, A.; Karski, E.E.; Allen, I.E.; DuBois, S.G.; Haas-Kogan, D.A.
- Book ID
- 127060497
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 75 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0360-3016
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π SIMILAR VOLUMES
Between 7/3/80 and 5/7/86 we gave 32 of our neuroblastoma patients 62 diagnostic doses of metaiodobenzylguanidine (MIBG) and 12 patients 20 treatment doses. Our conclusion from our diagnostic dose studies is that MIBG should be used for staging the extent of neuroblastoma before therapy is started,
## Abstract ## BACKGROUND ^131^Iβmetaiodobenzylguanidine (^131^IβMIBG) is selectively taken up by cells of neural crest origin, allowing targeted radiotherapy of tumors such as neuroblastoma (NB) and pheochromocytoma. Radiotherapy may provide additional benefits in the treatment of NB, with modera