The novel enol formate formula IV has been proposed recently' as the constitution of l&a luciferin, the specific substrate in the bioluminescence enzyme (luciferme) system of the fresh water Ii-t Latia neritoides.
Bioluminescence activity of Latia luciferin analogs
β Scribed by Satoshi Kojima; Shojiro Maki; Takashi Hirano; Yoshihiro Ohmiya; Haruki Niwa
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 131 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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BIOLlEilNlSCENCE of Cypridina hilgendorfii (Japenese name:umi-hotaru) has been studied extensively since 1917, when Harvey (1) observed the luciferin-luciferase reaction with extracts of this animal. The luminescent system of Cypridina is one of the simplest among luminous animals and plantc 60 far
A total synthesis of Cypridina luciferin (I), a bioluminescent substance obtained from Cypridina hilgendorfii (l), was achieved in 1966 (2) by reductive condensation of an appropriate 2-aminopyrazine derivative and a-keto acid, but the yield was too low to use th!s route for preparative purposes. Tw
CYPRIDINA luciferin (I) has been shoosn to have the structure represented by Ia (1). We wish to report in this oommunioation a total.