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Biology of anchoring fibrils: lessons from dystrophic epidermolysis bullosa

✍ Scribed by Leena Bruckner-Tuderman; Bianca Höpfner; Nadja Hammami-Hauasli


Book ID
117640619
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
945 KB
Volume
18
Category
Article
ISSN
0945-053X

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Collagenase and stromelysin expression in recessive dystrophic epidermolysis bullosa (RDEB) was studied at both the protein and the gene expression levels in fibroblast cultures. The amount of enzyme protein in the culture medium, as determined using a specific enzyme assay, showed a 9.7-fold increa