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Biologically active TGF-β1 is increased in cerebrospinal fluid while it is reduced in serum in multiple sclerosis patients

✍ Scribed by J. D. Rollnik; E. Sindern; C. Schweppe; J. P. Malin


Book ID
109336633
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
503 KB
Volume
96
Category
Article
ISSN
0001-6314

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Nitric oxide (NO) is hypothesized to play a role in the immunopathogenesis of multiple sclerosis (MS). Increased levels of NO metabolites have been found in patients with MS. Peroxynitrite, generated by the reaction of NO with superoxide at sites of inflammation, is a strong oxidant capable of damag