Convenient Syntheses and Biological Acti
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Sandra LΓΆhr; Carsten Jacobi; Andre Johann; Gerhard Gottschalk; ArminΒ de Meijere
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Article
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2000
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John Wiley and Sons
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English
β 261 KB
π 1 views
A series of Ο-trans-(bicyclopropyl)-substituted fatty acids 9 has been synthesized from bicyclopropylidene (5) starting by deprotonation with n-butyllithium. Electrophilic substitution of lithiobicyclopropylidene with THP-protected Ο-iodoalkanols 6 gave the THP-protected (bicyclopropylidenyl)alkanol