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Biological effects of cocaine derivatives I: Improved synthesis and pharmacological evaluation of norcocaine

✍ Scribed by Ronald F. Borne; John A. Bedford; Judith L. Buelke; Cathy B. Craig; Thomas C. Hardin; Arthur H. Kibbe; Marvin C. Wilson


Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
243 KB
Volume
66
Category
Article
ISSN
0022-3549

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The synthesis and biological activity of a series of azatricyclodecane analogues of cocaine are described. All compounds studied in this series exhibit nanomolar potency and good selectivity for the serotonin transporter versus the dopamine transporter.