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Biological Effects of a New Vacuolar-H,+-ATPase Inhibitor in Colon Carcinoma Cell Lines

✍ Scribed by Rosanna Supino; A. Ivana Scovassi; Anna Cleta Croce; Laura Dal Bo; Enrica Favini; Alessandro Corbelli; Carlo Farina; Paola Misiano; Franco Zunino

Book ID
111399189
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
455 KB
Volume
1171
Category
Article
ISSN
0890-6564

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## Abstract Bafilomycin A1, a specific inhibitor of V‐ATPases, is a potent inhibitor of bone resorption, but the underlying mechanisms of its action remain unclear. In this study, we investigated the effect of Bafilomycin A1 on endocytosis and apoptosis in RAW cells and RAW cell‐derived osteoclasts