Antitumor effect of a new selective matr
โ
A. Matsushita; M. Onda; E. Uchida; R. Maekawa; T. Yoshioka
๐
Article
๐
2001
๐
John Wiley and Sons
๐
French
โ 402 KB
The antitumor effect of a new matrix metalloproteinase inhibitor, MMI-166, which is a selective inhibitor of MMP-2 and -9, was examined in the hamster pancreatic cancer cell line PGHAM-1. In vitro, MMI-166 inhibited the gelatinase activity of MMP-2 and -9 derived from PGHAM-1 cells, and dose-depende