𝔖 Bobbio Scriptorium
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Biological conversion of 17α-hydroperoxyprogesterone to 11α,17α-dihydroxyprogesterone

✍ Scribed by Liat Tan; Pierre Falardeau


Book ID
118851633
Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
345 KB
Volume
41
Category
Article
ISSN
0006-291X

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The antifungal ketoconazole affects testosterone synthesis in dispersed rat testicular cells. In the presence of ketoconazole an accumulation of 17 alpha,20 alpha-dihydroxyprogesterone has been observed. This steroid was isolated from the testis of Wistar rats after a [4-14C]progesterone incorporati