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Biological and physicochemical evaluation of the conformational stability of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

โœ Scribed by Yu Seok Youn; Min Jae Shin; Su Young Chae; Cheng-Hao Jin; Tae Hyung Kim; Kang Choon Lee


Book ID
106363813
Publisher
Springer Netherlands
Year
2007
Tongue
English
Weight
298 KB
Volume
29
Category
Article
ISSN
0141-5492

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## Abstract Tumor necrosis factor (TNF) is a cytokine that mediates tumor necrosis. To date, 20 different members of the TNF superโ€family and 21 different receptors have been identified. All ligands of the TNF superโ€family have been found to activate transcription factor NFโ€ฮบB and cโ€Jun kinase. Mem