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Biological and clinical implications of the MTHFR C677T polymorphism

✍ Scribed by Per Magne Ueland; Steinar Hustad; Jørn Schneede; Helga Refsum; Stein Emil Vollset

Book ID
117340532
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
194 KB
Volume
22
Category
Article
ISSN
0165-6147

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## Abstract **BACKGROUND:** We investigated whether infants with homozygous genotype TT of the __MTHFR__ gene were at increased risk of severe mental retardation. **METHODS:** One hundred children with severe mental retardation (cases) were investigated from a large geographic‐based study of infant