No coin nor oath required. For personal study only.
Cover Photograph: Artists impression of a Saqqiq (ancient Eskimo), by Nuka Godtfredsen: The recent sequencing of a complete βpalaeoeskimoβ genome marks another milestone in the analysis of ancient human DNA, but also raises questions of cost and scientific limitations. As Shapiro and Hofreiter comment in this issue, it is an impressive achievement, but sequencing of just a fraction of the genome β hence accommodating the limitations of the short fragments in ancient DNA, and reducing the prohibitive cost β might well reveal a sufficient number of polymorphic positions (SNPs) to elucidate the origins of modern peoples. Many other aspects of genome sequencing are covered in this paper that takes us from a 4000 year old hair sample to modern humans living in Southern Africa.
π SIMILAR VOLUMES
**Cover Photograph:** Confocal microscopy image of a section of a chicken heart showing a developing coronary vessel and the surrounding myocardium. The section was immunolabeled for Tbx5 (shown in green), Pdlim7 (shown in red), and counterβstained with DAPI to show nuclei (blue). In cells of the le
Images show blastema formation in wing discs that have been cultured for 2 days. Immunostaining reveals mitotic cells (red, stained with anti-HP3), JNK activation (green, staining of puckered (puc) expression) and the dorsal-ventral boundary (blue, stained with anti-Senseless). SPIM (Selective Plane
**Cover Photograph:** Could imaginal discs in insects prove to be an important model for regenerative biology? Authors from Barcelona, Spain, present a summary of current research into imaginal disc regeneration and discuss the power of this tissue as a tool for understanding the genetics of regener
The recipe for primordial soup: acid or bitter, hot or warm. JBS Haldane's concept of life arising from a "primordial soup" in a bowl riven by lightning still appeals to cartoonists making dinosaur movies, but it's scientifically moldy after 80 years. Studies on the origin of life are increasingly p