Biodistribution of radiolabeled monoclonal antibody after intraperitoneal administration in nude mice with hepatic metastasis from human colon cancer
โ Scribed by Kazuhiko Yoshida; Touru Fujikawa; George Yoshizawa; Akihiro Tanabea; Kenji Sakurai
- Book ID
- 112290107
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 575 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1436-2813
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The biodistribution and pharmacokinetics of 2 monoclonal antibodies (MAbs) specific for ovarian carcinoma, O C I25 and OV-TL3, were studied in nude mice bearing intraperitoneally (i.p.) growing human ovarian carcinoma xenografts of NIH:OVCAR-3. The ovarian carcinoma xenografts grew as non-adherent c
The rate of catabolism of a radiolabelled monoclonal anti-CEA antibody has been compared with that of control IgG1 in control nude mice and in mice with CEA producing xenografts and antigen negative xenografts. The rate of catabolism of antibody, but not of IgG, was increased 3-4 fold in mice with x