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Biodistribution and radiation absorbed dose of (N-methyl[11C])pyrilamine: a histamine H-1 receptor radiotracer

✍ Scribed by Yanai, Kazuhiko; Dannals, Robert F.; Wilson, Alan A.; Ravert, Hayden T.; Scheffel, Ursula; Tanada, Shuji; Wagner, Henry N.


Book ID
122641688
Publisher
Elsevier Science
Year
1989
Weight
312 KB
Volume
16
Category
Article
ISSN
0883-2897

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(N-[11C]-Methyl)doxepin: Synthesis of a
✍ Hayden T. Ravert; Robert F. Dannals; Alan A. Wilson; Henry N. Wagner Jr. πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 French βš– 208 KB

## Abstract Doxepin (3‐dibenz [b,e] oxepin ‐ 11(6H) ‐ ylidene ‐ N,N ‐ dimethyl ‐ 1 ‐ propanamine), a potent H~1~ histamine antagonist, was labeled with ^11^C‐iodomethane by N‐alkylation of normethyldoxepin. The synthesis, purification, and formulation were performed in approximately 20 minutes with