Biodegradable PLGA based nanoparticles for sustained regional lymphatic drug delivery
✍ Scribed by Deepa A. Rao; M. Laird Forrest; Adam W.G. Alani; Glen S. Kwon; Joseph R. Robinson
- Book ID
- 102398664
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 217 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0022-3549
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📜 SIMILAR VOLUMES
## Abstract Novel ‘nano in nano’ composites consisting of biodegradable polymer nanoparticles incorporated into polymer nanofibers may efficiently modulate drug delivery. This is shown here using a combination of model compound‐loaded biodegradable nanoparticles encapsulated in electrospun fibers.
## Abstract **BACKGROUND:** Drug delivery systems (DDS) were designed using insulin as model drug and poly (lactic–co‐glycolic) copolymers (PLGA) as polymeric matrix. The carriers were synthesized by direct self‐assembly of the insulin and the polyester under mild conditions. **RESULTS:** The kind