Biodegradable high-molecular-weight multiblock polymers based on poly(ethylene glycol) for drug delivery
✍ Scribed by Alena Braunová; Michal Pechar; Karel Ulbrich
- Book ID
- 113692444
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 219 KB
- Volume
- 132
- Category
- Article
- ISSN
- 0168-3659
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📜 SIMILAR VOLUMES
Biodegradable polymer vesicle for drug delivery is reported. Poly(3-caprolactone)-block-poly(ethyl ethylene phosphate) with well-defined structure (PCL 150 -b-PEEP 30 ) has been prepared by ring-opening polymerization. It forms vesicles in aqueous solution using the thin-film hydration method and fu
## Abstract Thermosensitive PNVCL‐__b__‐PEG block copolymer coupled with folic acid was prepared as an anti‐cancer drug carrier. This polymer self‐assembled into stable micelles in aqueous solutions at above 33 °C. At 37 °C, the release profile of PNVCL‐__b__‐PEG‐FA micelles showed a slower and mor
A new thermosensitive hydrogel was designed and prepared by simply mixing N- [(2-hydroxy-3-trimethylammonium) propyl] chitosan chloride (HTCC) and poly(ethylene glycol) (PEG) with a small amount of a-b-glycerophosphate (a-b-GP). The optimum preparative condition was investigated, and the obtained fo