Biocompatibility of poly(2,4-pentadiene-1-ol)

✍ Scribed by Ulbrich, K. ;?princl, L. ;Kope?ek, J.

• Publisher: John Wiley and Sons
• Year: 1974
• Tongue: English
• Weight: 858 KB
• Volume: 8
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/jbm.820080205

✦ Synopsis

Abstract

In our earlier papers^1–4^ we reported on the biocompatibility of esters and substituted amides of methacrylic and acrylic acids which are suitable for the development of specific biological functions.^5^ The results described in these papers^1–4^ enabled some relationships to be formulated which exist between the chemical and physical structure of the implants, on the one hand, and the process of their healing‐in and calcification, on the other.^6^.

A number of biological applications require materials having rubber‐like mechanical properties. With this aim we started in our laboratory the development of hydrophilic elastomers based on dienes containing hydrophilic groups. Poly(2,4‐pentadiene‐1‐ol)^7^ was the first polymer of this type obtained which had mechanical properties suited for biomedical applications. Its biocompatibility with living tissue is reported in this paper.