𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Biocompatibility of Nanofilm-Encapsulated Silicone and Silicone-Hydrogel Contact Lenses

✍ Scribed by Hirotsugu Yasuda

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
280 KB
Volume
6
Category
Article
ISSN
1616-5187

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Summary: A material placed in or in contact with a biological system, that causes the minimum perturbation that can be tolerated by the host biological system, can be considered to be biocompatible. The major effects caused by a contact lens can be considered to be 1) the blocking of the natural supply of oxygen to the epithelium cells of the cornea, 2) interference with the normal evaporation of water from the tear fluid layer, and 3) hindrance of the normal functions of blinking for replenishing oxygen‐saturated tear fluid and removing dead epithelium cells, which result from apoptosis. The encapsulation of a highly oxygen‐permeable contact lens by a nanofilm with an imperturbable surface state minimizes all these terms. The encapsulated contact lens can be worn safely in extended wear.
magnified image

📜 SIMILAR VOLUMES

Measurement errors related to contact an
Measurement errors related to contact angle analysis of hydrogel and silicone hydrogel contact lenses
✍ Michael L. Read; Philip B. Morgan; Carole Maldonado-Codina 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB

## Abstract This work sought to undertake a comprehensive investigation of the measurement errors associated with contact angle assessment of curved hydrogel contact lens surfaces. The contact angle coefficient of repeatability (COR) associated with three measurement conditions (image analysis COR,

Dynamic in vitro dehydration patterns of
Dynamic in vitro dehydration patterns of unworn and worn silicone hydrogel contact lenses
✍ J. M. González-Méijome; A. López-Alemany; J. B. Almeida; M. A. Parafita 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 343 KB

## Abstract __Purpose:__ To evaluate the effect of wear on dynamic __in vitro__ dehydration of silicone hydrogel (Si‐Hi) contact lens (CL) using a previously described gravimetric procedure. __Methods:__ Five different silicone hydrogel (Si‐Hi) contact lenses (CL) were evaluated after being worn by

Comparative study of silicone-hydrogel c
Comparative study of silicone-hydrogel contact lenses surfaces before and after wear using atomic force microscopy
✍ M. Lira; L. Santos; J. Azeredo; E. Yebra-Pimentel; M. Elisabete C. D. Real Olive 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 408 KB

## Abstract __Purpose:__ The aim of this study was to analyze surface changes of three silicone‐hydrogel contact lenses after daily wear. The lenses used in this study were balafilcon A, lotrafilcon B (both surface‐treated), and galyfilcon A (non surface‐treated). __Methods:__ To understand how and

In vitro water wettability of silicone h
In vitro water wettability of silicone hydrogel contact lenses determined using the sessile drop and captive bubble techniques
✍ Carole Maldonado-Codina; Philip B. Morgan 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB

## Abstract This study investigated the water contact angles of five commercially available silicone hydrogel contact lenses (Acuvue Advance, Acuvue Oasys, Focus Night & Day, O~2~ Optix, and PureVision) using sessile drop and captive bubble techniques. The only lens type that showed a significant d

Surface wettability enhancement of silic
Surface wettability enhancement of silicone hydrogel lenses by processing with polar plastic molds
✍ Lai, Yu-Chin ;Friends, Gary D. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

In the quest for hydrogel contact lenses with improved extended wear capability, the use of siloxane moieties in the lens materials was investigated. However, the introduction of hydrophobic siloxane groups gave rise to wettability and lipidlike deposit problems. It was found that when polysiloxane-

Equivalences between refractive index an
Equivalences between refractive index and equilibrium water content of conventional and silicone hydrogel soft contact lenses from automated and manual refractometry
✍ José M. González-Méijome; Antonio López-Alemany; Madalena Lira; José B. Almeida; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB

## Abstract ## Purpose The purpose of the present study was to develop mathematical relationships that allow obtaining equilibrium water content and refractive index of conventional and silicone hydrogel soft contact lenses from refractive index measures obtained with automated refractometry or eq