Biochemical Response to Ursodeoxycholic Acid Predicts Long-Term Outcome in Japanese Patients With Primary Biliary Cirrhosis: A Validation Study
β Scribed by Azemoto, Nobuaki ;Kumagi, Teru ;Abe, Masanori ;Konishi, Ichiro ;Matsuura, Bunzo ;Hiasa, Yoichi ;Onji, Morikazu
- Book ID
- 122324201
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 119 KB
- Volume
- 140
- Category
- Article
- ISSN
- 0016-5085
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π SIMILAR VOLUMES
Biochemical response to ursodeoxycholic acid (UDCA) in patients with primary biliary cirrhosis (PBC) is variable. It has been recently proposed that an alkaline phosphatase (ALP) decline of more than 40% in baseline value or a normal level after 1 year of UDCA treatment (Barcelona criteria) could se
We read with interest the article by Corpechot et al. in a recent issue of HEPATOLOGY. 1 Corpechot et al. identify the absence of a biochemical response to ursodeoxycholic acid (UDCA) as an important predictive factor for death or liver transplantation in patients with primary biliary cirrhosis (PBC