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BIOCHEMICAL RESPONSE TO URSODEOXYCHOLIC ACID AND LONG-TERM PROGNOSIS IN PRIMARY BILIARY CIRRHOSIS

✍ Scribed by L. Abenavoli; C. Corpechot; N. Rabahi; Y. Chrétien; T. Andreani; C. Johanet; O. Chazouilleres; F. Luzza; G. Gasbarrini; R. Poupon

Book ID
119633130
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
87 KB
Volume
41
Category
Article
ISSN
1590-8658

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Biochemical response to ursodeoxycholic acid (UDCA) in patients with primary biliary cirrhosis (PBC) is variable. It has been recently proposed that an alkaline phosphatase (ALP) decline of more than 40% in baseline value or a normal level after 1 year of UDCA treatment (Barcelona criteria) could se

Comment on biochemical response to ursod
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We read with interest the article by Corpechot et al. in a recent issue of HEPATOLOGY. 1 Corpechot et al. identify the absence of a biochemical response to ursodeoxycholic acid (UDCA) as an important predictive factor for death or liver transplantation in patients with primary biliary cirrhosis (PBC