๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Biochemical Pharmacology


Book ID
109598800
Publisher
Nature Publishing Group
Year
1958
Tongue
English
Weight
124 KB
Volume
182
Category
Article
ISSN
0028-0836

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Cytosine arabinoside (Ara-C) is a very potent inhibitor of DNA synthesis in mammalian cells. This inhibition does not appear to be due to the direct inhibition of DNA polymerase by Ara-CTP (triphosphate of Ara-C) because it is a very weak competitive inhibitor of this enzyme. The inhibition of DNA s