Progress and limitations in the use of i
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Mark Gumbleton; Kenneth L. Audus
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Article
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2001
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John Wiley and Sons
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English
β 200 KB
π 1 views
A relatively simple, widely applicable, and robust in vitro method of predicting blood-brain barrier (BBB) permeability to central nervous system-acting drugs is an increasing need. A cell-based model offers the potential to account for transcellular and paracellular drug diffusional processes, meta