๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2

โœ Scribed by Christopher Jonathan Daraius Austin; B. M. Mailu; G. J. Maghzal; A. Sanchez-Perez; S. Rahlfs; K. Zocher; H. J. Yuasa; J. W. Arthur; K. Becker; R. Stocker; N. H. Hunt; H. J. Ball

Publisher
Springer
Year
2010
Tongue
English
Weight
991 KB
Volume
39
Category
Article
ISSN
0939-4451

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

S-Benzylisothiourea derivatives as small
S-Benzylisothiourea derivatives as small-molecule inhibitors of indoleamine-2,3-dioxygenase
โœ Kenji Matsuno; Kazushige Takai; Yoshinobu Isaka; Yuka Unno; Masayuki Sato; Osamu ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 416 KB

S-Benzylisothiourea 3a was discovered by its ability to inhibit indoleamine-2,3-dioxygenase (IDO) in our screening program. Subsequent optimization of the initial hit 3a lead to the identification of sub-lM inhibitors 3r and 10h, both of which suppressed kynurenine production in A431 cells. Synthesi