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Biochemical and connective tissue changes in cyclophosphamide-induced lung fibrosis in rats

✍ Scribed by Narayanan Venkatesan; Durairaj Punithavathi; Gowri Chandrakasan

Book ID
113994196
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
542 KB
Volume
56
Category
Article
ISSN
0006-2952

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## Abstract ## Background Connective tissue growth factor (CTGF) is a highly profibrogenic molecule implicated in hepatic fibrogenesis. Small interfering RNA (siRNA) is an effective tool to silence gene expression post‐transcriptionally. Therefore, we conducted an investigation to determine if int