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Bioavailability and Pharmacokinetics of Microencapsulated 1,3-Dichloropropene in Rats

✍ Scribed by W.T. Stott; J.R. Gilbert; R.J. McGuirk; K.A. Brzak; L.M. Alexander; M.D. Dryzga; A.L. Mendrala; M.J. Bartels

Book ID
112268708
Publisher
Oxford University Press
Year
1998
Tongue
English
Weight
127 KB
Volume
41
Category
Article
ISSN
1096-6080

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In a pharmacokinetic study, 15, 30, 60, and 150 mg kg-' intravenous and oral doses of methocarbamol were administered to rats. Differences observed in plasma clearance values, i.e. 0~0203,0~0156,0~0123, and 0-0085 1 kg-' min-' for 15,30,60, and 150 mg kg-', respectively, suggested a dosedependent ph