𝔖 Bobbio Scriptorium
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Bioactive Peptides from Epibiotic Pseudoalteromonas Strain P1

✍ Scribed by Chellaram, C.; Anand, T. Prem; Shanthini, C. Felicia; Kumar, B. Arvind; Sarma, Siddath P.


Book ID
119191058
Publisher
Elsevier
Year
2012
Weight
489 KB
Volume
2
Category
Article
ISSN
2212-6708

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Bioactive hydroxyethylene dipeptide isos
✍ Vittorio Rasetti; N.Claude Cohen; Heinrich RΓΌeger; Richard GΓΆschke; JΓΌrgen Maiba πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 426 KB

The design and synthesis of new truncated 8-amino hydroxyethylene dipeptide isosteres lacking the P4-P2 peptide backbone is described. The most active compounds 15c and 30c inhibited human renin in the submicromolar range. This promising concept may offer the possibility to discover completely non-p