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Bio-morphological events in the development of the human female mammary gland from fetal age to puberty

โœ Scribed by A. G. Naccarato; Paolo Viacava; Silvana Vignati; Giovanni Fanelli; Angelo G. Bonadio; Giancarlo Montruccoli; Generoso Bevilacqua


Publisher
Springer
Year
2000
Tongue
English
Weight
942 KB
Volume
436
Category
Article
ISSN
1432-2307

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The nuclear transcription factor of activated T cells (NFAT) suggested to be a tumor suppressor. Here we report that two out of three NFATc3ร€/ร€ and two in four NFATc3รพ/ร€ female mice developed aggressive mammary adenocarcinoma by 12.5 and 16 mo of age, respectively, with no occurrences in age-matched