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Binding study of p-hydroxybenzoic acid esters to bovine serum albumin by fluorescent probe technique

โœ Scribed by H. W. Jun; R. T. Mayer; C. M. Himel; L. A. Luzzi


Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
581 KB
Volume
60
Category
Article
ISSN
0022-3549

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Structure relationship for binding of su
โœ Par-Lin Hsu; Joseph K. H. Ma; H. W. Jun; Louis A. Luzzi ๐Ÿ“‚ Article ๐Ÿ“… 1974 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 458 KB

The binding constants and the number of binding sites for the binding of 11 sulfonamide and seven penicillin derivatives to bovine serum albumin were determined using a fluorescence probe method. The results demonstrate that these drugs bind to hydrophobic sites on the serum albumin. The binding aff