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Binding sites of a novel neuropeptide pituitary-adenylate-cyclase-activating polypeptide in the rat brain and lung

✍ Scribed by Hing-Chung LAM; Kazuhiro TAKAHASHI; Mohammed A. GHATEI; Sandip M. KANSE; Julia M. POLAK; Stephen R. BLOOM


Book ID
115128242
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
438 KB
Volume
193
Category
Article
ISSN
1432-1327

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The biochemical characteristics and the distribution of pituitary adenylate cyclaseactivating polypeptide (PACAP) binding sites have been investigated in the brain of the frog Rana ridibunda by using [ 125 I]PACAP27 as a radioligand. Membrane-binding studies revealed the existence of high-affinity r