Effect of substrate binding loop mutatio
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Koustav Maity; Tanushree Banerjee; Narayanappa Prabakaran; Namita Surolia; Avadh
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Article
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2011
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John Wiley and Sons
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English
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## Abstract Enoyl acyl carrier protein reductase (ENR), which catalyzes the final and rate limiting step of fatty acid elongation, has been validated as a potential drug target. Triclosan is known to be an effective inhibitor for this enzyme. We mutated the substrate binding site residue Ala372 of