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Binding of psychoactive drugs to rat brain amine receptors, measured ex vivo, and their effects on the metabolism of biogenic amines

✍ Scribed by Hans R. Burki

Book ID
112346927
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
846 KB
Volume
332
Category
Article
ISSN
0028-1298

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✍ T. A. Pugsley; W. Lippmann πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 631 KB

Pyrroxan (20 mg/kg, i.p.) , a new potential antianxiety agent, increased brain norepinephrine (NE) turnover in rats, reflecting a possible central e-adrenergic receptor blocking activity, in contrast, chlordiazepoxide (20 mg/kg, i.p.), a widely used antianxiety agent, did not alter the NE turnover.