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Effect of pentoxifylline and aminophylline on biogenic amine metabolism of the rat brain

✍ Scribed by Daniel P. Cardinali

Book ID
118322991
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
306 KB
Volume
47
Category
Article
ISSN
0014-2999

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Effects of pyrroxan and chlordiazepoxide
Effects of pyrroxan and chlordiazepoxide on biogenic amine metabolism in the rat brain
✍ T. A. Pugsley; W. Lippmann πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 631 KB

Pyrroxan (20 mg/kg, i.p.) , a new potential antianxiety agent, increased brain norepinephrine (NE) turnover in rats, reflecting a possible central e-adrenergic receptor blocking activity, in contrast, chlordiazepoxide (20 mg/kg, i.p.), a widely used antianxiety agent, did not alter the NE turnover.