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Binding of azide ion to methemoglobin at elevated temperatures and the reality of the “compensation” temperature

✍ Scribed by A. C. I. Anusiem; G. B. Ogunmola; J. G. Beetlestone

Publisher
Wiley (John Wiley & Sons)
Year
1977
Tongue
English
Weight
268 KB
Volume
16
Category
Article
ISSN
0006-3525

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✦ Synopsis

Abstract

We have studied the binding of azide ion to ferrihemoglobin at elevated temperatures. Up to a temperature of 45°C there is no difference in the ligand binding behavior of hemoglobin when compared with the results obtained at lower temperatures. The compensation temperature Tc of 290.6 ± 5.3°K, obtained in this study within the temperature range 303–318°K, confirms that the compensation pattern obtained by Lumry and Rajender is not dependent on the temperature range of the experiment but an intrinsic property of the protein conformation.

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