Binding of (125I) triiodothyronine to human peripheral leukocytes and its internalization
✍ Scribed by Z. Kostrouch; V. Felt; I. Raška; J. Nedvídková; E. Holečková
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 566 KB
- Volume
- 43
- Category
- Article
- ISSN
- 1420-682X
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## Abstract To investigate the binding of interferon to human lymphoid cells, we purified human α interferon and radio‐labelled it with iodine −125. Binding at 4°C could be saturated and was inhibited by unlabelled interferon; it was specific for cells of human origin. Dissociation constants for th
i y ; 11 Life Sciences Division, Ceri 4-Hydroxynonenal (HNE) is produced during peroxidation of polyunsaturated fatty acids. It exerts a chemokinetic effect on human polymorphonuclear leukocytes (PMN). Investigations of this mechanism were performed. The results indicate that [3H]-HNE binding to PMN