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Binding Energy and Catalysis: The Implications for Transition-State Analogs and Catalytic Antibodies

✍ Scribed by Mader, Mary M.; Bartlett, Paul A.


Book ID
126193069
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
620 KB
Volume
97
Category
Article
ISSN
0009-2665

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## Abstract __The effective design of catalytic antibodies represents a major conceptual and practical challenge. It is implicitly assumed that a proper transition state analogue (TSA) can elicit a catalytic antibody (CA) that will catalyze the given reaction in a similar way to an enzyme that woul