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Binding and Melting of D-Loops by the Bloom Syndrome Helicase †

✍ Scribed by van Brabant, Anja J.; Ye, Tian; Sanz, Maureen; German, James L.; Ellis, Nathan A.; Holloman, William K.

Book ID
125981752
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
140 KB
Volume
39
Category
Article
ISSN
0006-2960

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Localization of the bloom syndrome helic
Localization of the bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: Comparison with the werner's syndrome helicase
✍ Vazganoush Gharibyan; Hagop Youssoufian 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 475 KB 👁 2 views

The Bloom (BLM) and Werner's (WRN) syndrome proteins may regulate recombination and DNA repair. Using a novel polyclonal antibody to human BLM, we detected the 170-kda BLM antigen in wild-type but not Bloom syndrome cells. BLM was localized to punctate nuclear structures. The level of BLM but not WR