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Binderless granulation of pharmaceutical lactose powders

โœ Scribed by Katsura Takano; Kazuo Nishii; Akiko Mukoyama; Yuki Iwadate; Hidehiro Kamiya; Masayuki Horio


Book ID
114079464
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
471 KB
Volume
122
Category
Article
ISSN
0032-5910

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Effect of process parameters on the melt
โœ G.M. Walker; G. Andrews; D. Jones ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 175 KB

Co-melt granulation of lactose and PEG was investigated in a fluidised bed granulator. The effect of process parameters such as binder content and binder viscosity were correlated to granulation time and particle size distribution. The experimental data indicated that after initial nucleation the gr