Feedback control in high shear granulation of pharmaceutical powders
โ Scribed by Satoru Watano; Tetsuya Numa; Ichiro Koizumi; Yoshifumi Osako
- Book ID
- 117639240
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 537 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0939-6411
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A mechanistic understanding of the over-granulation problem during high shear wet granulation (HSWG) process can guide efficient development of robust formulation and manufacturing process. Using microcrystalline cellulose (MCC) as a model compound, we demonstrate that size enlargement is an importa
Theoretical and experimental evidence is given to show that steady states can be reached during agglomerate growth and break-up in high-shear granulation of fine powders. An earlier theoretical model [G.I. Tardos, I.M. Khan and P.R. Mort, Critical parameters and limiting conditions in binder granula