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Bim mediates apoptosis of CD127lo effector T cells and limits T cell memory

✍ Scribed by Sara Wojciechowski; Michael B. Jordan; Yanan Zhu; Janice White; Allan J. Zajac; David A. Hildeman


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
491 KB
Volume
36
Category
Article
ISSN
0014-2980

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Previous investigations have defined phenotypic differences between unprimed (naive) and antigen-primed (memory) T cells from human peripheral blood. We now report that memory T cells proliferate much more than naive cells when stimulated with anti-CD3 monoclonal antibody or pairs of antLCD2 monoclo