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Expression of inhibitory "killer cell lectin-like receptor G1" identifies unique subpopulations of effector and memory CD8 T cells

✍ Scribed by Niklas B. Beyersdorf; Xin Ding; Klaus Karp; Thomas Hanke


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
232 KB
Volume
31
Category
Article
ISSN
0014-2980

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In cancer patients, NK cell inhibitory receptors (IR) are expressed on a fraction of melanomaspecific lymphocytes with a unique reactivity for tumor antigens derived from normal, nonmutated genes (differentiation antigens). It is presently not known whether expression of these receptors is induced d