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Bilirubin metabolism in gunn rats treated with phenobarbital

โœ Scribed by Nagasawa, S. ;Robinson, Stephen H.

Book ID
105605887
Publisher
Springer-Verlag
Year
1972
Tongue
English
Weight
61 KB
Volume
7
Category
Article
ISSN
0435-1339

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Jaundiced Gunn rats, treated with phenobarbital (60 mg per kg i.p. for 7 to 10 days) showed 25 and 36% decreases in mean plasma bilirubin levels in two experiments (p < 0.01). Kinetic studies with tracer 14C-bilirubin revealed that there was no change in bilirubin turnover or total pool size due to