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Influence of phenobarbital treatment on p-nitrophenol and bilirubin glucuronidation in Wistar rat, Gunn rat and cat

✍ Scribed by P.L.M. Jansen; P.Th. Henderson


Book ID
115771451
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
468 KB
Volume
21
Category
Article
ISSN
0006-2952

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Effects of phenobarbital on bilirubin me
✍ Arnold N. Cohen; Jaime Kapitulnik; J. Donald Ostrow; Eugene A. Zenone; Cecile Co πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 810 KB

Jaundiced Gunn rats, treated with phenobarbital (60 mg per kg i.p. for 7 to 10 days) showed 25 and 36% decreases in mean plasma bilirubin levels in two experiments (p < 0.01). Kinetic studies with tracer 14C-bilirubin revealed that there was no change in bilirubin turnover or total pool size due to