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Biliary excretion of copper in fischer rats treated with copper salt and in long-evans cinnamon (LEC) rats with an inherently abnormal copper metabolism

โœ Scribed by Naoki Sugawara; Dan Li; Michihiro Katakura; Chieko Sugawara


Book ID
112894933
Publisher
Humana Press Inc
Year
1994
Tongue
English
Weight
505 KB
Volume
46
Category
Article
ISSN
0163-4984

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The Long-Evans Cinnamon rat is a mutant strain that contracts hereditary hepatitis and, eventually, spontaneous hepatocellular carcinoma. Because we found a corresponding gross copper accumulation in the liver of the rats, we examined whether the development of hepatitis in our rat system could be p