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Bilateral deep brain stimulation of the globus pallidus internus in tardive dystonia

✍ Scribed by Wataru Sako; Satoshi Goto; Hideki Shimazu; Nagako Murase; Kazuhito Matsuzaki; Tetsuya Tamura; Hideo Mure; Yusuke Tomogane; Norio Arita; Hiroo Yoshikawa; Shinji Nagahiro; Ryuji Kaji

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
540 KB
Volume
23
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

Tardive dystonia is a disabling movement disorder as a consequence of exposure to neuroleptic drugs. We followed 6 patients with medically refractory tardive dystonia treated by bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) for 21 ± 18 months. At last follow‐up, the Burke‐Fahn‐Marsden Dystonia Rating Scale (BFMDRS) motor score improved by 86% ± 14%, and the BFMDRS disability score improved by 80% ± 12%. Bilateral GPi‐DBS is a beneficial therapeutic option for the long‐term relief of tardive dystonia. © 2008 Movement Disorder Society

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