<p>This contributed volume explores the emerging intersection between big data analytics and genomics. Recent sequencing technologies have enabled high-throughput sequencing data generation for genomics resulting in several international projects which have led to massive genomic data accumulation a
Big Data Analytics in Genomics
โ Scribed by Ka-Chun Wong (eds.)
- Publisher
- Springer
- Year
- 2016
- Tongue
- English
- Leaves
- 426
- Edition
- 1st ed.
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
โฆ Table of Contents
Front Matter....Pages i-viii
Front Matter....Pages 1-1
Introduction to Statistical Methods for Integrative Data Analysis in Genome-Wide Association Studies....Pages 3-23
Robust Methods for Expression Quantitative Trait Loci Mapping....Pages 25-88
Causal Inference and Structure Learning of GenotypeโPhenotype Networks Using Genetic Variation....Pages 89-143
Genomic Applications of the NeymanโPearson Classification Paradigm....Pages 145-167
Front Matter....Pages 169-169
Improving Re-annotation of Annotated Eukaryotic Genomes....Pages 171-195
State-of-the-Art in SmithโWaterman Protein Database Search on HPC Platforms....Pages 197-223
A Survey of Computational Methods for Protein Function Prediction....Pages 225-298
Genome-Wide Mapping of Nucleosome Position and Histone Code Polymorphisms in Yeast....Pages 299-313
Front Matter....Pages 315-315
Perspectives of Machine Learning Techniques in Big Data Mining of Cancer....Pages 317-336
Mining Massive Genomic Data for Therapeutic Biomarker Discovery in Cancer: Resources, Tools, and Algorithms....Pages 337-355
NGS Analysis of Somatic Mutations in Cancer Genomes....Pages 357-372
OncoMiner: A Pipeline for Bioinformatics Analysis of Exonic Sequence Variants in Cancer....Pages 373-396
A Bioinformatics Approach for Understanding GenotypeโPhenotype Correlation in Breast Cancer....Pages 397-428
โฆ Subjects
COMPUTERS / Databases / Data mining;Big data;Genomics;Data mining;Quantitative research -- Social aspects
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