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Bifunctional chiral synthons via biochemical methods. : VII. Optically-active 2.2′-dihydroxy-1,1′-binaphthyl.

✍ Scribed by Shih-Hsiung Wu; Li-Qing Zhang; Ching-Shih Chen; Gary Girdaukas; C.J. Sih


Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
199 KB
Volume
26
Category
Article
ISSN
0040-4039

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A versatile chemical-microbiological approach has been developed for the preparation of chiral a-hydroxy aldehydes via stereoselective reduction of the corresponding a-keto thioacetals or via optical resolution of the racemic a-acetoxy esters. As part of our continued interest in the preparation of