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Bicyclic Compounds Derived from Tartaric Acid and α-Amino Acids (BTAas): Synthesis of New Molecular Scaffolds Derived from the Combination of (R,R)-Tartaric Acid and L-Serine

✍ Scribed by Nicoletta Cini; Fabrizio Machetti; Gloria Menchi; Ernesto G. Occhiato; Antonio Guarna


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
355 KB
Volume
2002
Category
Article
ISSN
1434-193X

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Pyroglutamic acid derivative (I) is proved to be an excellent chiral starting compound for the synthesis of title amino acids (IX), (X), and (V). The syntheses are based on a combination of methods previously used for the preparation of 4-and 5-substituted prolines. These methods are the ring openin