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Biased T cell receptor Vα region repertoire in the synovial fluid of rheumatoid arthritis patients

✍ Scribed by Gerd Pluschke; Gesa Ricken; Heiko Taube; Susanne Kroninger; Inga Melchers; Hans Hartmut Peter; Klaus Eichmann; Ulrich Krawinkel


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
868 KB
Volume
21
Category
Article
ISSN
0014-2980

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Ia+ T Cells in Synovial Fluid And Tissue
✍ Gerd R. Burmester; David T. Y. Yu; Anne-Marie Irani; Henry G. Kunkel; Robert J. 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 607 KB

## Abstract Markedly elevated levels of T cells expressing Ia antigens were found in the synovial membranes and synovial fluids of patients with rheumatoid arthritis. The primary increase in expression of the la antigens was on the OKT 8+ (suppressor/cytotoxic) T cell subset. In addition, the total