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Bias and variance of extrapolated tails for area-under-the-curve (AUC) and area-under-the-moment-curve (AUMC)

✍ Scribed by Robert D. Purves


Book ID
112473255
Publisher
Springer
Year
1992
Tongue
English
Weight
427 KB
Volume
20
Category
Article
ISSN
1573-8744

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A limited sampling model has been developed for Β―unarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (C max ). The model was developed using training data sets f